HGH 191AA, commonly known as Somatropin, is a recombinant form of human growth hormone comprising the full 191 amino acid sequence identical to endogenous pituitary-derived GH. Its complete amino acid chain distinguishes it from truncated or modified analogues, making it a highly relevant reference compound in growth hormone research.
Mechanistically, HGH 191AA binds to the GH receptor, triggering downstream JAK2/STAT5 signalling cascades that regulate IGF-1 production in the liver. This in turn mediates anabolic processes including protein synthesis, lipolysis, and longitudinal bone growth — all areas of active investigation in endocrinology and metabolic disease research.
In preclinical studies, HGH 191AA has been examined across a broad range of applications, including growth hormone deficiency models, body composition studies, wound healing, and age-related metabolic decline. It is also frequently utilised in cell culture and in vivo models to characterise GH receptor dynamics and downstream signalling pathways.
Reconstitute with bacteriostatic water. Store lyophilised peptide at -20°C; once reconstituted, store at 4°C and use within 4 weeks. Avoid repeated freeze-thaw cycles.
Molecular Formula
C₉₉₀H₁₅₂₉N₂₆₃O₃₀₁S₇
Molecular Weight
22,124 g/mol
Purity
>98%
CAS Number
12629-01-5
Form
Lyophilised Powder
Research Applications
Growth hormone deficiency models, IGF-1 signalling research, metabolic disease studies, body composition research, wound healing studies, endocrinology and receptor dynamics
For research purposes only. Not for human use.


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