Melanotan 2 (MT-2) Acetate is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), designed to bind melanocortin receptors — primarily MC1R, MC3R, MC4R, and MC5R — with high affinity. Originally developed at the University of Arizona, MT-2 has become one of the most extensively researched melanocortin agonists in preclinical science.
In research settings, MT-2 is primarily investigated for its role in melanogenesis, where MC1R activation stimulates eumelanin production in melanocytes, producing a darkening of skin pigmentation. Separately, MC4R agonism has drawn significant interest in studies relating to energy homeostasis, appetite suppression, and body weight regulation. MT-2 has also been studied in models of sexual function, particularly erectile response and libido, via central nervous system MC4R pathways.
Peptician supplies MT-2 Acetate as a lyophilised powder for maximum stability. Recommended storage is at -20°C, protected from light and moisture. Upon reconstitution with bacteriostatic water, store at 4°C and use within 4 weeks.
Molecular Formula
C₅₀H₆₉N₁₅O₉
Molecular Weight
1024.18 g/mol
Purity
>98%
CAS Number
121062-08-6
Form
Lyophilised Powder
Research Applications
Melanogenesis and pigmentation research, melanocortin receptor pharmacology, appetite and energy homeostasis, sexual function and erectile response models, obesity and metabolic research, neuropeptide signalling
For research purposes only. Not for human use.
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