GLP-1 (7-36) Amide is a 30-amino acid incretin peptide derived from the post-translational processing of proglucagon in intestinal L-cells. As one of the most extensively studied metabolic peptides in contemporary endocrinology research, GLP-1 exerts its effects primarily through binding to the GLP-1 receptor (GLP-1R), a G-protein coupled receptor expressed in pancreatic beta cells, the central nervous system, the gastrointestinal tract, and cardiac tissue.
Upon receptor activation, GLP-1 stimulates glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety signalling in hypothalamic pathways. These multifaceted mechanisms have made it a central subject in metabolic disease research, particularly in studies relating to type 2 diabetes, obesity, and cardiovascular function.
This 5mg research-grade preparation of GLP-1 (7-36) Amide is supplied as a lyophilised powder with a purity of greater than 98% as assessed by HPLC. Molecular formula: C₁₄₉H₂₂₄N₄₀O₄₅. Molecular weight: 3297.7 g/mol. CAS number: 89750-14-1.
For optimal stability, store lyophilised peptide at -20°C, protected from light and moisture. Once reconstituted, aliquot and store at -80°C to minimise freeze-thaw degradation.
Molecular Formula
C₁₄₉H₂₂₄N₄₀O₄₅
Molecular Weight
3297.7 g/mol
Purity
>98%
CAS Number
89750-14-1
Form
Lyophilised Powder
Research Applications
Metabolic disease research, Type 2 diabetes models, Obesity and appetite regulation, Insulin secretion studies, Cardiovascular function research, Neuroprotection and CNS signalling
For research purposes only. Not for human use.
Reviews
There are no reviews yet.