HGH Fragment 176-191 is a synthetic peptide analogue comprising amino acids 176 to 191 of the human growth hormone (hGH) sequence. Unlike full-length hGH, this fragment retains the lipolytic activity associated with the C-terminal region whilst lacking the growth-promoting and insulin-desensitising effects of the parent hormone, making it a highly selective research tool.
In preclinical studies, HGH Fragment 176-191 has been shown to stimulate lipolysis and inhibit lipogenesis through mechanisms that appear to be independent of the IGF-1 pathway. Research suggests it may interact with beta-3 adrenergic receptors to promote fat oxidation, making it a subject of significant interest in metabolic and obesity research.
Key research applications include adipose tissue metabolism, lipid oxidation pathways, body composition studies, and comparative analyses against full-length growth hormone peptides. Its high selectivity and well-characterised sequence make it a reliable reference compound in endocrinology and metabolic research settings.
Storage: Store at -20°C. Protect from light and moisture. Reconstitute with bacteriostatic water for in vitro use.
Molecular Formula
C₇₈H₁₂₅N₂₃O₂₃S₂
Molecular Weight
1817.1 g/mol
Purity
>98% (HPLC)
CAS Number
221231-10-3
Form
Lyophilised Powder
Research Applications
Lipid metabolism research, Lipolysis and lipogenesis studies, Adipose tissue biology, Obesity and metabolic syndrome research, Growth hormone receptor pharmacology, Body composition studies
For research purposes only. Not for human use.
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