Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue receptor (GHSR) agonist, recognised for its ability to stimulate growth hormone (GH) release with a high degree of selectivity. Unlike broader-acting secretagogues, Ipamorelin does not significantly elevate cortisol, prolactin, or ACTH levels, making it a valuable research tool for studies requiring isolated GH pathway activation.
The peptide functions by mimicking the action of ghrelin at the GHSR, triggering pulsatile GH secretion from the anterior pituitary gland. This mechanism makes it particularly useful in studies examining the somatotropic axis, age-related GH decline, and metabolic regulation.
Research applications include investigations into body composition changes, bone density, tissue repair, and sleep physiology, where GH signalling plays a central role. Ipamorelin has also been studied in the context of gastrointestinal motility due to its structural relationship to ghrelin.
Store at -20°C, protected from light and moisture. Reconstitute using bacteriostatic water prior to use in experimental settings.
Molecular Formula
C₃₈H₄₉N₉O₅
Molecular Weight
711.85 g/mol
Purity
>98%
CAS Number
170851-70-4
Form
Lyophilised Powder
Research Applications
Growth hormone secretion studies, Metabolic and body composition research, Bone density and skeletal research, Tissue repair and regeneration, Sleep physiology, Gastrointestinal motility research
For research purposes only. Not for human use.
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