Nicotinamide Adenine Dinucleotide (NAD+) is a critical coenzyme found in all living cells, playing a central role in redox reactions, energy metabolism, and cellular signalling pathways. As a hydride-transfer agent, NAD+ shuttles electrons during glycolysis, the citric acid cycle, and oxidative phosphorylation, making it indispensable to mitochondrial ATP production. Beyond its metabolic function, NAD+ serves as a substrate for sirtuins (SIRT1–SIRT7), poly(ADP-ribose) polymerases (PARPs), and CD38, linking its availability directly to DNA repair, gene expression regulation, and inflammatory response modulation.
Research interest in NAD+ has grown substantially in the context of ageing biology, where declining intracellular NAD+ levels have been associated with mitochondrial dysfunction, impaired cellular senescence pathways, and metabolic disorders. Preclinical studies have investigated NAD+ repletion strategies in models of neurodegeneration, metabolic syndrome, and cardiovascular dysfunction.
Peptician’s NAD+ 5,000 IU is supplied as a lyophilised powder with a purity of >98%, suitable for use in cell culture, biochemical assays, and in vivo animal model research. Molecular Formula: C₂₁H₂₇N₇O₁₄P₂. Molecular Weight: 663.43 g/mol. CAS Number: 53-84-9. Store at –20°C, protected from light and moisture. Reconstitute in sterile water immediately prior to use.
Molecular Formula
C₂₁H₂₇N₇O₁₄P₂
Molecular Weight
663.43 g/mol
Purity
>98%
CAS Number
53-84-9
Form
Lyophilised Powder
Research Applications
Cellular energy metabolism, DNA repair and genomic stability, Sirtuin activation and ageing biology, Mitochondrial function research, Neurodegeneration models, Metabolic syndrome and obesity research
For research purposes only. Not for human use.
Reviews
There are no reviews yet.