Semax is a heptapeptide analogue of the adrenocorticotropic hormone (ACTH) fragment 4-7, with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Originally developed in Russia, it has been extensively investigated in preclinical and clinical research contexts for its pronounced neuroprotective and nootropic properties.
The peptide is believed to act by modulating brain-derived neurotrophic factor (BDNF) expression and its receptor TrkB signalling pathways, as well as influencing dopaminergic and serotonergic neurotransmission. Research suggests Semax may upregulate the expression of genes associated with the immune response and neuronal survival, making it of significant interest in neuroscience research.
Key areas of investigation include ischaemic stroke models, cognitive function studies, attention and memory research, and neuroprotection following central nervous system injury. It has also been explored in models of optic nerve disease and anxiety regulation.
Storage: Store at -20°C. Protect from light and moisture. Once reconstituted, store at 4°C and use within 48–72 hours.
Molecular Formula
C₃₇H₅₁N₉O₁₀S
Molecular Weight
813.9 g/mol
Purity
>98%
CAS Number
80714-61-0
Form
Lyophilised Powder
Research Applications
Neuroprotection, Cognitive function research, Stroke and ischaemia models, BDNF pathway modulation, Neurodegenerative disease models, Anxiety and stress response research
For research purposes only. Not for human use.
Reviews
There are no reviews yet.