Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment 4-7, with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Originally developed in Russia, it has been the subject of extensive preclinical and clinical research focused on its neuroprotective, nootropic, and neurotrophic properties.
Semax is believed to exert its effects primarily through modulation of the brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) signalling pathways, alongside interaction with melanocortin receptors. Research suggests it may upregulate neurotrophic factor expression, promote neuronal survival, and support synaptic plasticity, making it a compound of significant interest in neuroscience research.
Key areas of investigation include ischaemic stroke models, cognitive function studies, attention and memory research, and neuroprotection following oxidative stress. It has also been studied in the context of anxiety and stress response modulation in preclinical models.
Specifications: Molecular Formula: C₃₇H₅₁N₉O₁₀S | Molecular Weight: 813.93 g/mol | Purity: >98% (HPLC) | CAS Number: 80714-61-0 | Form: Lyophilised Powder.
Storage: Store at -20°C upon receipt. Protect from light and moisture. Stable for up to 24 months when stored correctly.
Molecular Formula
C₃₇H₅₁N₉O₁₀S
Molecular Weight
813.93 g/mol
Purity
>98%
CAS Number
80714-61-0
Form
Lyophilised Powder
Research Applications
Neuroprotection, Cognitive Function Research, Neurotrophic Factor Modulation, Ischaemic Stroke Models, Stress Response Research, Synaptic Plasticity
For research purposes only. Not for human use.
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