Epitalon (also known as Epithalamin) is a synthetic tetrapeptide composed of the amino acid sequence Ala-Glu-Asp-Gly. Originally derived from the pineal gland extract Epithalamin, it has become one of the most widely studied peptides in longevity and anti-ageing research. Its primary mechanism of action involves the activation of telomerase, an enzyme responsible for elongating telomeres — the protective caps at the ends of chromosomes that shorten with each cell division. By stimulating telomerase activity, Epitalon is investigated for its potential to slow cellular ageing and extend cell lifespan in vitro.
Beyond telomere biology, research has explored Epitalon’s role in regulating melatonin secretion via the pineal gland, modulating circadian rhythm, and influencing neuroendocrine function. Studies have also examined its antioxidant properties and potential role in reducing oxidative stress at the cellular level.
Epitalon 10mg is supplied as a lyophilised powder with a purity of >98%, molecular formula C₁₄H₂₂N₄O₉, and a molecular weight of 390.35 g/mol. CAS number: 307297-39-8. Store at -20°C, protected from light and moisture. Reconstitute with sterile bacteriostatic water prior to use in experimental settings.
Molecular Formula
C₁₄H₂₂N₄O₉
Molecular Weight
390.35 g/mol
Purity
>98%
CAS Number
307297-39-8
Form
Lyophilised Powder
Research Applications
Telomere biology, Anti-ageing and longevity research, Neuroendocrine regulation, Circadian rhythm modulation, Antioxidant and oxidative stress studies, Pineal gland function research
For research purposes only. Not for human use.
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