Mazdutide (IBI362) is a novel dual agonist peptide targeting both glucagon-like peptide-1 (GLP-1) and glucagon receptors, developed to investigate combined metabolic signalling pathways. By simultaneously activating GLP-1 receptors to enhance insulin secretion and suppress appetite, and glucagon receptors to increase energy expenditure and hepatic glucose output, mazdutide offers researchers a compelling tool for studying the interplay between these two complementary pathways in metabolic regulation.
In preclinical and clinical research settings, mazdutide has demonstrated significant interest in the areas of obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD/MASH). Its dual receptor activity is thought to produce additive or synergistic effects on bodyweight reduction and glycaemic control compared to single-receptor agonists, making it a valuable compound for comparative metabolic research.
Each vial contains 5mg of mazdutide supplied as a lyophilised powder with a purity of >98% as determined by HPLC. The molecular formula is C₁₁₅H₁₇₄N₃₀O₃₄S, with a molecular weight of approximately 2,572.8 g/mol. CAS number: 2382191-47-9. Store lyophilised product at -20°C, protected from light and moisture. Once reconstituted, store at 4°C and use within 72 hours.
Molecular Formula
C₁₁₅H₁₇₄N₃₀O₃₄S
Molecular Weight
2572.8 g/mol
Purity
>98%
CAS Number
2382191-47-9
Form
Lyophilised Powder
Research Applications
Obesity and adiposity research, Type 2 diabetes and glycaemic regulation, Non-alcoholic fatty liver disease (NAFLD/MASH), Energy expenditure and thermogenesis, GLP-1 and glucagon receptor pharmacology, Metabolic syndrome research
For research purposes only. Not for human use.


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