Pinealon (EDR) is a short peptide bioregulator consisting of the tripeptide sequence Glu-Asp-Arg (glutamic acid–aspartic acid–arginine). Originally developed by the St Petersburg Institute of Bioregulation and Gerontology, Pinealon is designed to exert a selective regulatory effect on neurons and pineal gland tissue, making it a compelling subject in studies of neurological function, cognitive ageing, and circadian rhythm regulation.
As a peptide bioregulator, Pinealon is theorised to interact with nuclear chromatin and modulate gene expression in neuronal cells, potentially promoting cellular homeostasis and neuroprotection. Research has explored its involvement in antioxidant activity, melatonin-pathway modulation, and the attenuation of age-related neuronal decline.
Key research applications include investigation into neurodegenerative mechanisms, brain ageing, circadian biology, and pineal gland physiology. It has also been studied alongside other peptide bioregulators in longevity research protocols.
Storage: Store at -20°C upon receipt, protected from light and moisture. Stable for 24 months when stored correctly. Reconstitute in bacteriostatic water prior to use in laboratory settings.
Molecular Formula
C₁₃H₂₂N₆O₉
Molecular Weight
422.35 g/mol
Purity
>98%
CAS Number
427869-40-7
Form
Lyophilised Powder
Research Applications
Neuroprotection research, Cognitive ageing studies, Circadian rhythm and melatonin pathway investigation, Pineal gland physiology, Longevity and bioregulator research, Neurodegenerative disease mechanisms
For research purposes only. Not for human use.


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