Semaglutide 15mg – 10 vials

Semaglutide is a synthetic analogue of glucagon-like peptide-1 (GLP-1), a naturally occurring incretin hormone involved in the regulation of insulin secretion, appetite suppression, and energy homeostasis. Structurally, semaglutide shares approximately 94% sequence homology with native human GLP-1, with strategic modifications — including a C18 fatty diacid chain attached via a linker — that confer exceptional resistance to dipeptidyl peptidase-4 (DPP-4) degradation and extend its plasma half-life significantly compared to endogenous GLP-1.

In research settings, semaglutide has been extensively investigated for its actions at the GLP-1 receptor, where it stimulates glucose-dependent insulin release, suppresses glucagon secretion, and slows gastric emptying. Central nervous system studies have also examined its role in hypothalamic appetite regulation and reward pathway modulation. Additional areas of active investigation include cardiovascular protection, hepatic lipid metabolism, neuroinflammation, and potential neuroprotective effects.

This 15mg vial is supplied as a lyophilised powder with a purity of >98% as verified by HPLC. Molecular formula: C₁₈₇H₂₉₁N₄₅O₅₉. Molecular weight: 4,113.6 g/mol. CAS number: 910463-68-2. Recommended storage is at -20°C in a dry environment; reconstituted solution should be kept at 4°C and used within 28 days.

For research purposes only. Not for human use.