Tesamorelin is a synthetic analogue of endogenous growth hormone-releasing hormone (GHRH), comprising the full 44-amino acid sequence of GHRH with a trans-3-hexenoic acid group conjugated to the N-terminus.
This modification enhances stability against enzymatic degradation, prolonging its biological activity compared to native GHRH.
In research settings, tesamorelin has been extensively studied for its capacity to stimulate the pituitary gland to produce and release endogenous growth hormone in a physiologically regulated, pulsatile manner.
Unlike exogenous growth hormone administration, tesamorelin preserves the natural feedback mechanisms of the hypothalamic-pituitary axis.
Key areas of scientific investigation include its effects on visceral adipose tissue reduction, metabolic function, body composition, and lipid profiles. It has also attracted research interest in cognitive function, cardiovascular risk factors, and age-related hormonal decline.
Store lyophilised peptide at -20°C, protected from light and moisture. For research purposes only. Not for human use.
Molecular Formula
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight
5135.9 g/mol
Purity
>98%
CAS Number
901758-09-6
Form
Lyophilised Powder
Research Applications
Growth hormone secretion, Visceral adipose tissue reduction, Metabolic function and body composition, Lipid profile modulation, Cognitive function research, Hypothalamic-pituitary axis regulation
For research purposes only. Not for human use.
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