Tesamorelin is a synthetic peptide analogue of endogenous growth hormone-releasing hormone (GHRH), comprising the full 44-amino acid sequence of GHRH with a trans-3-hexenoic acid modification at the N-terminus that enhances stability and bioactivity. It functions by binding to pituitary GHRH receptors, stimulating the pulsatile release of endogenous growth hormone (GH) in a physiologically consistent manner, which in turn promotes IGF-1 production.
In research settings, Tesamorelin has been extensively studied for its effects on body composition, particularly the selective reduction of visceral adipose tissue (VAT). It has also attracted significant interest in metabolic research, cognitive function studies, and investigations into GH axis modulation. Research has explored its utility in models of lipodystrophy, metabolic syndrome, and age-related GH decline.
Recommended storage is at -20°C in a dry environment, away from direct light. Once reconstituted, store at 4°C and use within 28 days.
Molecular Formula
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight
5135.9 g/mol
Purity
>98%
CAS Number
218949-48-5
Form
Lyophilised Powder
Research Applications
Growth hormone axis modulation, Visceral adipose tissue reduction, Metabolic syndrome research, Lipodystrophy models, Cognitive function studies, IGF-1 pathway investigation
For research purposes only. Not for human use.


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