Tesamorelin is a synthetic analogue of endogenous growth hormone-releasing hormone (GHRH), consisting of the full 44-amino acid GHRH sequence stabilised by a trans-3-hexenoic acid modification at the N-terminus. This modification enhances resistance to enzymatic degradation, improving the peptide’s stability and half-life compared to native GHRH.
In research settings, Tesamorelin has been extensively studied for its ability to stimulate the pituitary gland to release endogenous growth hormone (GH) in a pulsatile, physiologically consistent manner. Unlike exogenous GH administration, Tesamorelin preserves the natural feedback mechanisms of the hypothalamic-pituitary axis, making it a subject of significant scientific interest.
Research has explored Tesamorelin’s effects on visceral adipose tissue reduction, metabolic function, lipid profiles, and body composition. It has also attracted attention in studies examining cognitive function, IGF-1 modulation, and age-related decline in GH secretion.
Storage: Store at -20°C. Keep away from light and moisture. Reconstitute with bacteriostatic water prior to use in laboratory settings.
Molecular Formula
C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight
5135.8 g/mol
Purity
>98%
CAS Number
218949-48-5
Form
Lyophilised Powder
Research Applications
Growth hormone secretion studies, Visceral adiposity and metabolic research, Body composition analysis, IGF-1 modulation research, Hypothalamic-pituitary axis studies, Cognitive function and ageing research
For research purposes only. Not for human use.
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