Thymosin Alpha 1 (Tα1) is a naturally occurring 28-amino acid peptide originally isolated from thymosin fraction 5 of bovine thymus tissue. It is endogenously produced in the thymus gland and plays a central role in the maturation, differentiation, and activation of T-lymphocytes, making it a subject of considerable interest in immunological research.
Mechanism of action studies indicate that Thymosin Alpha 1 modulates immune responses by stimulating the production and activity of T-helper cells, natural killer (NK) cells, and dendritic cells. It is also believed to upregulate cytokine expression, including interleukin-2 (IL-2) and interferon-gamma (IFN-γ), thereby enhancing adaptive immunity.
Research applications for Thymosin Alpha 1 include immunodeficiency models, infectious disease research, oncology, vaccine adjuvant studies, and investigations into autoimmune conditions. It has also been explored in the context of chronic viral infections and as a potential modulator of inflammatory pathways.
Supplied as lyophilised powder. Store at -20°C, protected from moisture and light. Reconstitute with bacteriostatic water prior to use in research settings.
Molecular Formula
C₁₂₉H₂₁₅N₃₃O₅₅S
Molecular Weight
3108.5 g/mol
Purity
>98%
CAS Number
62304-98-7
Form
Lyophilised Powder
Research Applications
Immunology, Oncology, Infectious Disease Research, Vaccine Adjuvant Studies, Autoimmune Disease Research, T-Cell Biology
For research purposes only. Not for human use.
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