Gonadorelin Acetate is a synthetic decapeptide identical in structure to endogenous gonadotropin-releasing hormone (GnRH), the hypothalamic neuropeptide responsible for stimulating the anterior pituitary gland to secrete luteinising hormone (LH) and follicle-stimulating hormone (FSH). As a direct GnRH receptor agonist, gonadorelin binds to GnRH receptors on pituitary gonadotroph cells, triggering downstream signalling cascades that regulate gonadal steroid biosynthesis and reproductive function.
In research settings, Gonadorelin Acetate is widely used to investigate hypothalamic-pituitary-gonadal (HPG) axis dynamics, pituitary responsiveness, and the neuroendocrine regulation of reproduction. It serves as a valuable tool in studies examining LH and FSH secretion kinetics, gonadal feedback mechanisms, and the pharmacology of GnRH receptor agonism and antagonism.
Each vial contains 5mg of Gonadorelin Acetate supplied as a lyophilised powder with a purity of >98% as determined by HPLC analysis. Molecular formula: C₅₅H₇₅N₁₇O₁₃·xC₂H₄O₂. Molecular weight: approximately 1182.3 g/mol (free base). CAS number: 71447-49-9. Store at -20°C in a dry environment; once reconstituted, keep at 4°C and use within 7 days.
Molecular Formula
C₅₅H₇₅N₁₇O₁₃·xC₂H₄O₂
Molecular Weight
1182.3 g/mol
Purity
>98%
CAS Number
71447-49-9
Form
Lyophilised Powder
Research Applications
HPG axis regulation, pituitary function studies, reproductive endocrinology, LH and FSH secretion research, GnRH receptor pharmacology, neuroendocrine signalling
For research purposes only. Not for human use.
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