Human Menopausal Gonadotrophin (HMG) 75 IU is a purified gonadotrophin preparation derived from the urine of post-menopausal women, containing both follicle-stimulating hormone (FSH) and luteinising hormone (LH) activity in an approximate 1:1 ratio. Each vial is standardised to deliver 75 International Units of gonadotrophic activity, making it a widely referenced preparation in reproductive endocrinology research.
In research settings, HMG is employed to study the mechanisms of ovarian folliculogenesis, spermatogenesis, and the hypothalamic-pituitary-gonadal (HPG) axis. Its dual FSH and LH bioactivity allows investigators to examine synergistic gonadotrophin signalling, receptor binding kinetics, and downstream steroidogenic pathways in both male and female gonadal tissue models.
HMG 75 IU is supplied as a lyophilised powder for reconstitution, ensuring stability and potency during storage and handling. Purity exceeds 98% by HPLC analysis. The preparation should be stored at 2–8°C and protected from light; once reconstituted, it should be used promptly and not refrozen.
This product is intended solely for in vitro and preclinical laboratory investigation by qualified researchers.
Molecular Formula
N/A (complex glycoprotein mixture)
Molecular Weight
N/A (FSH ~34,000 g/mol; LH ~28,000 g/mol)
Purity
>98%
CAS Number
9002-68-0
Form
Lyophilised Powder
Research Applications
Reproductive endocrinology, Folliculogenesis research, Spermatogenesis studies, HPG axis signalling, Gonadotrophin receptor binding, Steroidogenesis research
For research purposes only. Not for human use.
Reviews
There are no reviews yet.